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Food Allergies vs. Food Sensitivities and the Immune System

by Dr. Anastasia Stocker

Understanding food allergies and food sensitivities and how they influence the immune system can be overwhelming. We are here to help make it more clear! The language we use to describe allergy versus sensitivity is used to understand what is happening in the immune system and what reactions or symptoms may be happening in your body.

Food Allergies:

Think of food allergies as your body’s hyperactive response to certain proteins found in food. When someone with a food allergy ingests a particular substance, the immune system perceives it as a threat and triggers an immediate reaction. This rapid response can manifest as hives, swelling, difficulty breathing, or even a life-threatening condition known as anaphylaxis.

Common food allergens include nuts, shellfish, eggs, and dairy. Food allergies primarily involve Immunoglobulin E (IgE), a type of antibody that plays a central role in allergic reactions. IgE triggers the release of histamine and other chemicals, leading to the swift onset of symptoms.

Food Sensitivities:

On the other hand, food sensitivities are a more subtle and delayed reaction to certain foods. Unlike allergies, sensitivities involve the immune system responding gradually, often over hours or days. This delayed response can make identifying the culprit a bit like searching for a needle in a haystack.

Symptoms of food sensitivities vary widely and may include digestive issues, headaches, fatigue, and skin problems. Food sensitivities are often associated with Immunoglobulin G (IgG), which plays a role in the immune system’s defense against infections. In the context of sensitivities, IgG mediates a more prolonged immune response.

The Role of Immunoglobulin A (IgA):

In addition to IgE and IgG, there’s another crucial player in the immune system called Immunoglobulin A (IgA). IgA is particularly relevant when it comes to the mucosal surfaces of the body, such as the digestive and respiratory tracts. It serves as the first line of defense against pathogens and plays a vital role in preventing the absorption of potentially harmful substances.

In the context of dietary responses, IgA is essential in maintaining gut health. Disruptions in IgA function can contribute to increased permeability of the intestinal lining, commonly known as “leaky gut.” This heightened permeability may lead to the development of food sensitivities, as undigested food particles and toxins can enter the bloodstream and trigger immune responses.

Distinguishing Features

Onset and Duration:

Allergies: Quick and immediate response, potentially life-threatening.

Sensitivities: Delayed reaction, symptoms may persist over an extended period.

Immune System Involvement:

Allergies: Immediate immune response involving IgE antibodies.

Sensitivities: Gradual immune response, involving IgG antibodies.

IgA: Crucial in maintaining mucosal health, particularly in the digestive system.

Symptomatology

Allergies: Pronounced symptoms like hives, swelling, and anaphylaxis.

Sensitivities: Varied symptoms, often subtle and chronic.

 

What Next?

Now that we’ve laid the groundwork for understanding the disparities between food allergies and sensitivities let’s explore some practical steps for managing each:

Allergies:

Identification: Undertake allergy testing to pinpoint specific triggers. Either skin-prick testing or blood tests.

Prevention: Strict avoidance of allergens is paramount.

Emergency Plan:Carry an epinephrine auto-injector for severe reactions.

Sensitivities

Elimination Diet: Remove potential culprits from your diet systematically. If you have autoimmune conditions we can use blood markers to identify if certain foods are aggravating your autoimmune disease. Reintroduction is necessary to assess whether a food is triggering your symptoms.

Food Diary: Track your food intake and symptoms to identify patterns.

Professional Guidance: Consult with a healthcare professional for comprehensive testing and guidance.

The intricate interplay of Immunoglobulins E, G, and A in the immune system highlights the complexity of our body’s responses to food. Recognizing these nuances can empower you to make informed choices that support your unique health journey. Remember, optimal wellness is a personalized and ongoing process. May your choices be nourishing, and may your journey be filled with vibrant health and vitality!

 

Want to know more or need more help? Schedule an appointment with one of our knowledgeable providers today!

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